MYC AMPLIFICATION AS A POTENTIAL MECHANISM OF PRIMARY RESISTANCE TO CRIZOTINIB IN ALK-REARRANGED NON-SMALL CELL LUNG CANCER: A BRIEF REPORT

MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report

INTRODUCTION: Translocations of the anaplastic lymphoma kinase (ALK) can be effectively targeted in advanced non-small cell lung cancer by ALK-TKI inhibitors including Crizotinib.However, the development of acquired resistance often limits the duration of Intakes these therapies.While several mechanisms of secondary resistance have been already ide

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Lidar Observations of the Swash Zone of a Low-Tide Terraced Tropical Beach under Variable Wave Conditions: The Nha Trang (Vietnam) COASTVAR Experiment

A field experiment was conducted at a tropical microtidal intermediate sandy beach with a low tide terrace (Nha Trang, Vietnam) to investigate the short-term Pancake swash-zone hydrodynamics and morphodynamics under variable wave conditions.Continuous 2D Lidar scanner observations of wave height at the lower foreshore, subsequent run-up and swash-i

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